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Proteomics Core


   During the past decade, the mass spectrometry-based proteomics technology platforms have emerged and evolved to be powerful tools for systemic analysis of proteins in biological samples. To facilitate biomedical research at Chang Gung University (CGU) and Chang Gung Memorial Hospital (CGMH), the Chang Gung Proteomics Core Laboratory (CGPCL) was established in CGU (9F, 1st Medical Science Building) in 2002. In 2005, CGPCL was further supported by the Molecular Medicine Research Center (MMRC) (Director, Dr. Yu-Sun Chang) at CGU to install several state-of-art mass spectrometers and then integrated into the MMRC as one of the functional core labs.


(1) Routine service for systematic protein identification and quantification

(2) R & D for proteomic technology platforms


   Application of proteomics technology platforms to discover disease-related molecules/cancer biomarkers

International Collaborations

1. International Cancer Biomarker Consortium (ICBC)

In 2005, the CGU Biomarker Team focused on the nasopharyngeal carcinoma biomarker discovery formally joined the International Cancer Biomarker Consortium (ICBC), which is organized and led by Dr. Lee Hartwell (President, Fred Hutchinson Cancer Research Center, FHCRC) to promote international collaboration on cancer biomarker discovery and validation using systemic approaches including proteomics. 

2. Dr. Christoph Borchers (Associate Professor, Department of Biochemistry and Microbiology University of Victoria, Victoria, BC, Canada; Director of UVic Genome BC Proteomics Centre) Collaborative project: MRM-based, multiplexed quantification of human proteins in clinical specimens.

3. Dr. Liang Li (Professor, Department of Chemistry, University of Alberta, Canada )

Collaborative project: Metabolome analysis of body fluids for disease biomarker discovery.

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